Safety Information

Last updated: June 9, 2026

PeriCalm Cascade™ is a dietary supplement designed to support women in perimenopause. It's built around seven clinically-anchored ingredients, including KSM-66® Ashwagandha and Pycnogenol®. Like any supplement, it's not right for everyone — and we want to be straight with you about that.

Read this page before starting PeriCalm Cascade. If anything here applies to you, talk to your doctor first.

Who should not take PeriCalm Cascade

Please do not take PeriCalm Cascade without first consulting your healthcare provider if you:

  • Are pregnant, breastfeeding, or trying to conceive
  • Have a history of hormone-sensitive cancer (breast, ovarian, uterine) or are currently being treated for one
  • Take SSRIs, SNRIs, or other antidepressant medications
  • Take thyroid medication (including levothyroxine)
  • Take blood thinners (warfarin, Eliquis, Xarelto, etc.)
  • Take immunosuppressants
  • Take sedatives or sleep medications
  • Have an autoimmune condition
  • Have liver, kidney, or thyroid disease
  • Are scheduled for surgery within the next two weeks
  • Are under 18 years old

This is not a complete list. If you take any prescription medication or have any ongoing medical condition, talk to your doctor before starting any new supplement.

Allergens and dietary information

PeriCalm Cascade is:

  • Gluten-free
  • Dairy-free
  • Soy-free
  • Non-GMO

It contains plant-based ingredients. Always read the full Supplement Facts label before use. If you have a known sensitivity to ashwagandha, pine bark, or any of the listed ingredients, do not take this product.

How to take it

Take 2 capsules daily with water, ideally with food. Most women take it in the morning, though some prefer evening. Consistency matters more than timing — daily use is what produces results.

Do not exceed the recommended dose. More is not better with adaptogens.

What to expect

Most women feel the first shift within 14 days — typically deeper sleep and a drop in the rage response. Full effects on cortisol regulation and hot flash frequency are typically observed within 30–60 days of consistent use.

If you don't feel the shift, our Feel-It-In-14-Days™ promise has you covered — see our Refund Policy.

Side effects

PeriCalm Cascade is generally well-tolerated. Some women report:

  • Vivid dreams in the first week (typically resolves within 7–10 days)
  • Mild digestive changes if taken on an empty stomach (take with food)
  • Drowsiness in the first few days (some women prefer evening dosing)

If you experience any unusual symptoms, stop taking the product and consult your doctor.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not use if the safety seal is broken or missing.

FDA disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Questions?

Email us at support@trypericalm.com. We are not your doctor, and we can't give medical advice — but if you have questions about whether PeriCalm Cascade is right for you, we're happy to share what we know so you can make an informed decision with your healthcare provider.